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Haichen Yang Selected Research

perampanel

1/2018Final safety, tolerability, and seizure outcomes in patients with focal epilepsy treated with adjunctive perampanel for up to 4 years in an open-label extension of phase III randomized trials: Study 307.
10/2017Perampanel with concomitant levetiracetam and topiramate: Post hoc analysis of adverse events related to hostility and aggression.
1/2017Effect of enzyme inhibition on perampanel pharmacokinetics: Why study design matters.
1/2017Analysis of falls in patients with epilepsy enrolled in the perampanel phase III randomized double-blind studies.
11/2016Pharmacokinetics, exposure-cognition, and exposure-efficacy relationships of perampanel in adolescents with inadequately controlled partial-onset seizures.
2/2016Cognitive effects of adjunctive perampanel for partial-onset seizures: A randomized trial.
1/2016Efficacy and tolerability of adjunct perampanel based on number of antiepileptic drugs at baseline and baseline predictors of efficacy: A phase III post-hoc analysis.
1/2016Adjunctive perampanel in adolescents with inadequately controlled partial-onset seizures: A randomized study evaluating behavior, efficacy, and safety.
8/2015Psychiatric and behavioral adverse events in randomized clinical studies of the noncompetitive AMPA receptor antagonist perampanel.
8/2015Lack of effect of perampanel on QT interval duration: Results from a thorough QT analysis and pooled partial seizure Phase III clinical trials.
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Haichen Yang Research Topics

Disease

27Seizures (Absence Seizure)
01/2018 - 05/2009
7Sleepiness
03/2020 - 05/2009
6Epilepsy (Aura)
01/2017 - 10/2010
6Dizziness (Lightheadedness)
02/2016 - 02/2015
5Headache (Headaches)
01/2016 - 11/2009
4Bipolar Disorder (Manic Depressive Psychosis)
09/2022 - 01/2019
4Mania (Manias)
11/2021 - 10/2016
3Fatigue
08/2015 - 11/2009
2Weight Gain
03/2020 - 02/2004
2Obsessive-Compulsive Disorder (Disorder, Obsessive-Compulsive)
01/2005 - 06/2003
2Social Phobia
02/2004 - 12/2003
1Fibrosis (Cirrhosis)
11/2020
1Major Depressive Disorder (Major Depressive Disorders)
10/2020
1Syndrome (Syndromes)
10/2020
1Hallucinations (Hallucination)
04/2019
1Psychotic Disorders (Schizoaffective Disorder)
01/2018
1Infections
01/2018
1Partial Epilepsies (Epilepsy, Partial)
01/2018
1Chronic Obstructive Pulmonary Disease (COPD)
05/2016
1Digestive System Diseases
07/2015
1Cholelithiasis
07/2015
1Treatment-Resistant Depressive Disorder
02/2012
1Vomiting
11/2009
1Nasopharyngitis
11/2009

Drug/Important Bio-Agent (IBA)

23perampanelIBA
01/2018 - 08/2012
9Anticonvulsants (Antiepileptic Drugs)IBA
10/2017 - 05/2009
8AMPA Receptors (AMPA Receptor)IBA
01/2017 - 08/2012
7Pharmaceutical PreparationsIBA
10/2020 - 08/2012
5AcidsIBA
01/2016 - 08/2012
5Levetiracetam (Keppra)FDA LinkGeneric
01/2012 - 05/2009
3Antipsychotic Agents (Antipsychotics)IBA
03/2020 - 01/2019
3Fluvoxamine (Luvox)FDA LinkGeneric
02/2004 - 06/2003
2Sertraline (Zoloft)FDA LinkGeneric
01/2018 - 05/2016
2EnzymesIBA
01/2017 - 05/2015
1Biomarkers (Surrogate Marker)IBA
09/2022
13,4-methylenedioxyethamphetamine (MDEA)IBA
11/2021
1MicroRNAs (MicroRNA)IBA
11/2020
1Transforming Growth Factors (Transforming Growth Factor)IBA
11/2020
1olanzapine-fluoxetine combination (Symbyax)FDA Link
03/2020
1Carbamazepine (Tegretol)FDA LinkGeneric
03/2020
1LithiumIBA
03/2020
1Olanzapine (Zyprexa)FDA Link
03/2020
1Quetiapine Fumarate (Seroquel)FDA Link
03/2020
1Lurasidone HydrochlorideFDA Link
03/2020
1Aripiprazole (Abilify)FDA Link
03/2020
1cariprazineIBA
03/2020
1asenapineFDA Link
03/2020
1XR 300IBA
03/2020
1Blood Glucose (Blood Sugar)IBA
04/2019
1Ceftriaxone (Ceftriaxon)FDA LinkGeneric
01/2018
1Risperidone (Risperdal Consta)FDA LinkGeneric
01/2018
1Antidepressive Agents (Antidepressants)IBA
10/2016
1TabletsIBA
05/2016
1alpha- Amino- 3- hydroxy- 5- methyl- 4- isoxazolepropionic Acid (AMPA)IBA
08/2015
1Excitatory Amino Acid AntagonistsIBA
08/2015
1Selective Serotonin Reuptake Inhibitors (Serotonin Reuptake Inhibitors)IBA
01/2005

Therapy/Procedure

8Therapeutics
01/2017 - 10/2010
1Drug Therapy (Chemotherapy)
03/2020
1Patient Readmission
04/2019
1Transcranial Magnetic Stimulation
02/2012